Description
Product Characteristics:
Dopamine-beta-Hydroxylase (DBH), Dopamine can be transformed into Noradrenalin. Conversion of dopamine to noradrenaline. [SUBUNIT] Homotetramer composed of two non-covalently bound disulfide-linked dimers. [SUBCELLULAR LOCATION] Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type II membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane, Single-pass type II membrane protein (Potential). Belongs to the copper type II ascorbate-dependent monooxygenase family.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: DBH, DBM, Dopamine beta hydroxylase, Dopamine- Beta-Hydroxylase, Dopamine beta monooxygenase, DOPO_RAT.
Target Information: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. [provided by RefSeq, Jul 2008]